EP-1227: Hypo-fractionated biological optimized dose-painting radiotherapy for high-risk prostate cancer
نویسندگان
چکیده
منابع مشابه
Dosimetric and Radiobiological Evaluation of Multiparametric MRI-guided Dose Painting in radiotherapy of Prostate Cancer
Introduction: Radiotherapy is one of the treatment options for locally advanced prostate cancer, however with standard radiation doses it is not always very effective. One of the strategies to improve the efficiency of radiotherapy is increasing the dose. In this study to increase tumor local control rates a new radiotherapy method, known as dose painting (DP) was investigated....
متن کاملClinical Results after High-Dose Intensity-Modulated Radiotherapy for High-Risk Prostate Cancer
Purpose. Patients with high-risk prostate cancer (PC) can be treated with high-dose intensity-modulated radiotherapy (IMRT) and long-term androgen deprivation (AD). In this paper we report on (i) late toxicity and (ii) biochemical (bRFS) and clinical relapse-free survival (cRFS) of this combined treatment. Methods. 126 patients with high-risk PC (T3-4 or PSA >20 ng/mL or Gleason 8-10) and ≥24 m...
متن کاملDosimetric and Radiobiological Evaluation of Multiparametric MRI-Guided Dose Painting in Radiotherapy of Prostate Cancer
Radiotherapy is one of the treatment options for locally advanced prostate cancer; however, with standard radiation doses, it is not always very effective. One of the strategies to improve the efficiency of radiotherapy is increasing the dose. In this study, to increase tumor local control rates, a new radiotherapy method, known as dose painting (DP), was investigated. To compare 3-dimensional ...
متن کاملRadical radiotherapy for high-risk prostate cancer in older men.
Historical data for older men with high-risk nonmetastatic prostate cancer treated with radiotherapy alone have demonstrated a 10-year prostate-cancer-specific mortality of around 30%. The development of dose escalation, using techniques such as intensity-modulated radiotherapy, has enabled more targeted delivery of treatment with improved efficacy and a reduction in the risk of toxicity compar...
متن کاملHypo-fractionated SBRT for localized prostate cancer: a German bi-center single treatment group feasibility trial
BACKGROUND For prostate cancer treatment, treatment options with minimal side effects are desired. External beam radiation therapy (EBRT) is non-invasive, standard of care and delivered in either conventional fractionation over 8 weeks or with moderate hypo-fractionation over about 5 weeks. Recent advances in radiotherapy technology have made extreme hypo-fractionated stereotactic body radiatio...
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ژورنال
عنوان ژورنال: Radiotherapy and Oncology
سال: 2015
ISSN: 0167-8140
DOI: 10.1016/s0167-8140(15)41219-8